Adult Zebrafish

fish

Zebrafish are an ideal system to discover genes that are essential for hematopoietic development in vivo.  The spectrum of blood cell types and the genes known to regulate normal hematopoiesis are well conserved between zebrafish and mammals, suggesting that the regulatory mechanisms directing lineage specification and differentiation are similar across vertebrate species.

Virtual Tour of Fish Facility

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Zebrafish Facility

facility

The Zebrafish Facility is a state-of-the-art aquatic system that occupies about 900 sq. ft. in the ground floor of the Reimann building. The space is divided into a food preparation room and two rooms containing zebrafish, which are an extension of the Laboratory Animal Facility (LAF) at Fox Chase Cancer Center. The Aquatic Habitats equipment automatically monitors water quality and houses up to 15,000 zebrafish in tanks of varying sizes. The rooms are climate controlled, have a strict day/night light cycle and are designed with positive air pressure to the hallway to maintain a clean environment. Dr. Harry Rozmiarek, D.V.M., Ph.D., is the Director of the Laboratory Animal Health Facility, and provides veterinary care. The facility manager is Alison Bilbee, who maintains the zebrafish and the aquatic infrastructure. Dr. Jennifer Rhodes is Director of the facility, and Center researchers can contact her for information relating to training services or use of zebrafish in the facility.

fishrow

The FCCC Inter-laboratory Zebrafish Meeting, FIZM, takes place on the last Friday of each month. Topics include zebrafish projects or resources at the Center. FCCC investigators that are currently using zebrafish or would like to start using the zebrafish model system are welcome to attend. For inquiries, contact Jennifer Rhodes. Additional information on core services can be found on our facility webpage.

The Rhodes Lab offers tours of the zebrafish facility upon request.