Development of HTS to identify inhibitors of Pak1
Hi, I'm Jami and I like robots. I developed a high-throughput screen that reports Pak kinase activity and used it to test a diverse library of over 40,000 drug-like compounds for inhibitors of Pak1 (p21-activated kinase 1). We found a number of compounds that disrupt Pak activity and are currently evaluating them and their mechanism of Pak1 inhibition. Oh, I live for Greek "dog songs" and Euro dance tracks. To seal the deal bring Borges, Lindemans Frambiose or Tobiko.