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BCRL Home » Research Projects » Estrogens and Breast Cancer » Related Publications

Estrogens and Breast Cancer

Related Publications
Estrogens and Breast Cancer

  1. Russo, J, Lareef M.H., Balogh, G. Guo, S., and Russo I.H. Estrogen and its metabolites are carcinogenic in human breast epithelial cells. J. of Steroid Biochemistry & Molecular Biology 87:1-25, 2003.
  2. Soares, R., Guo, S., Gartner, F., Schmitt, F.C. and Russo, J. estradiol-mediated vessel assembly and stabilization in tumor angiogenesis-b17 and EGFR crosstalk Angiogenesis 6:271-281,brequires TGF 2003
  3. Russo, J., Russo, I.H. Genotoxicity of Steroidal Estrogens. Trends in Endocrinology and Metabolism, 15(5):211-214, 2004.
  4. Soares R., Balogh, G., Guo S., Gartner, G.F., Russo J., and Schmitt, F. Evidence for the notch signaling pathway on the role of estrogen and angiogenesis. Molecular Endocrinology 18:1-10, 2004.
  5. Lareef, M.H. Garber, J. Russo, P.A., Russo, I.H., Heulings, R. and Russo, J. The estrogen antagonist ICI-182-780 does not inhibit the transformation phenotypes induced by -estradiol and 4-OH estradiol in human breast epithelial cells. Int. J. ofb17- Oncology 26:423-429, 2005.
  6. Fernandez, SV., Russo, IH., Lareef, MH., Balsara, B., and Russo, J. Comparative Genomic Hybridization of Human Breast Epithelial Cells Transformed by Estrogen and its Metabolites. Int J Oncol, 26(3):691-5,. 2005
  7. Chen, J-Q, Yager, J.D. and Russo, J. Regulation of mitochondrial respiratory chain structure and function by estrogens/estrogen receptors and potential physiological/pathophysiological implications: Review. Biochimica et Biophysica Acta XX: 1-17, 2005.
  8. Fernandez, S.V., Lareef, M.H., Russo, I.H., Balsara, B.R., Testa, J.R. and Russo, J. Estrogen and its metabolites 4-Hydroxy-estradiol induce mutations in TP53 and LOH in chromosome 13q12.3 near BRCA2 in human breast epithelial cells. International Journal of Cancer 118(8):1862-8, 2006.
  9. Cavalieri, E., Chakravarti, D., Guttenplan, J.,Hart, E., Ingle, J., Jankowiak, R., Muti, P., Rogan, E., Russo, J., Santen, R., Sutter, T. Catechol Estrogen Quinones as Initiators of Breast and Other Human Cancers. Implications for Biomarkers of Susceptibility and Cancer Prevention. Review. Biochimica et Biophysica Acta 1766:63-78, 2006
  10. Russo, J., Fernandez, S.V., Russo, P.A., Fernbaugh, R., Sheriff, F.S., Lareef, H.M.,Garber, J., and Russo,I.H. 17 beta estradiol induces transformation and tumorigenesis in human breast epithelial cells. FASEB J 20:1622-1634, 2006.
  11. Russo, J. and Russo, I.H. The role of estrogen in the initiation of breast cancer. The Journal of Steroid Biochemistry & Molecular Biology, 102:89-96, 2006 .
  12. Mello, M.L., Vidal, B.C., Lareef, M.H., Russo, I.H. and Russo, J. DNA content and estradiolbchromatin Texture of Human breast epithelial cells treated with 17- and the estrogen antagonist ICI 182,780 as assessed by Image Analysis. Mutation Research 617:1-7, 2007
  13. Tiezzi, D. G., Fernandez, S.V., Russo, J. Epithelial to Mesenchymal transition during breast cancer progression. Int J Oncol 31: 823-827, 2007
  14. Huang, Y., Fernandez, S., Goodwin, S., Russo, P.A., Russo, I. H., Sutter, T., and Russo, J. Epithelial to Mesenchymal Transition in Human Breast Epithelial Cells Transformed by 17- beta- Estradiol. Cancer Res 67 11147-11157, 2007.
  15. Harvey, J.A., Santen, R.J., Petroni, G. R., Bovbjerg, V., Smolkin, M.A., Sheriff, F. and Russo, J. Histology changes in the breast with menopausal hormone therapy use: correlation with breast density, ER, PgR, and proliferation indices. Menopause 15(1), 2008.

Abstracts Publications

  1. Lareef, M.H., Russo, I.H., Slater, C.M., Rogatko, A., and Russo, J.  Estrogen induces transformation phenotypes in the estrogen receptor negative MCF10F cells.  Proc. Am. Assoc. Cancer Res. 42:4743a, 2001.
  2. Lareef, H.M. Russo I.H. Sheriff, F., Slater, C. and Russo, J. Estrogen and its metabolites are carcinogenic in the human breast epithelial cells. Proc. Am. Assoc. Cancer Res. 43:2002.
  3. Lareef, M.H.; Russo, I.H., Sheriff, F., Tahin, Q. and Russo, J. Estrogen-receptor independent induction of loss of heterozygosity in human breast epithelial cells by estrogen and its metabolites. Breast Cancer Research and Treatment, 76: (Sup1)383a, 2002.
  4. Russo, J., Lareef, H., Tahin, Q. , and Russo, I.H. Pathways of carcinogenesis in the human breast. Climacteric: S1: S-27-02, 2002.
  5. Lareef, H.M. Russo I.H. Sheriff, F., Tahin, Q., and Russo, J. Genomic Changes induced by Estrogens in human breast epithelial cells (HBEC). Proc. Am. Assoc. Cancer Research. 44:904a, 2003.
  6. Russo, J.; Lareef, H.M.; Balogh, G.; Russo, I.H. Estrogen is a carcinogenic agent in the human breast. In. J. of Mol. Medicine 12: (Supp. 1) 147a, 2003.
  7. Fernandez, S.V., Lareef, M.H., Russo, I.H., Balsara, B.B., Testa, J. and Russo, J. Estrogen and its metabolite 4-OH-E2 induce LOH at 13q12.3, at a locus 0.8cM from the BRCA2 gene in human breast epithelial cells. Proc. Am. Assoc. Cancer Res.45:7a, 2004.
  8. Russo, P.A., Balogh, G.V., Russo, I.H., and Russo, J. Estrogen-induced transformation of human breast epithelial cells involves mutations in mismatch repair genes. Proc. Am. Assoc. Cancer Res.45:2629a, 2004.
  9. Lareef, M.H., Heulings, R., Russo, P.A., Garber, J., Russo, I.H., and Russo, J. The estrogen antagonist ICI-182-270 does not inhibit the proliferative activity and invasiveness induced in human breast epithelial cells by estradiol and its metabolite 4-OH-Estradiol. Proc. Am. Assoc. Cancer Res.45:11a, 2004.
  10. Mello, M.L., Vidal, B.C., Lareef, M.H., Russo, J. Image analysis of 17--estradiol-treated human breast epithelial cells. Proc. Am. Assoc. Cancer Res.45:8a, 2004.
  11. Balogh, G.V., Pastwa, E., Russo, I.H., Winters, T., Balsara, B. and Russo, J. DNA double
  12. Harvey, JA, Santen, RJ, Petroni, GR, Smolkin et al. Histology findings of Mammographically Dense Breast Tissue in Postmenopausal Women with and without Hormone Replacement Therapy, Breast Cancer Research and Treatment,  2004: 88: (Supplement 1),5008a.
  13. Vanegas, J., Russo, P.A., Russo, I.H., and Russo, J. Estrogen-Transformed Human Breast Epithelial Cells Exhibit an Altered Migratory Behavior in Vitro. Proc. Am. Assoc. Cancer Res.46: 2005.
  14. Fernandez, S.V., Russo, I.H. and Russo, J. Estrogen and its metabolites 4-hydroxy-estradiol and 2-hydroxy-estradiol induce mutation of p53 and LOH in a gene located 0.8cM of BCR2 in human breast epithelial cells. Proc. Am. Assoc. Cancer Res.46:2098a, 2005.
  15. Russo, P.A., Lareef, M.H., Garber, J., Russo, I.H., Fernandez, S., Fernbaugh, R., Balsara,B.R., Sheriff, F.,  Balogh, G.A., Mailo, D.,  Heulings, R.  Russo, J. An in Vitro-in Vivo Model of Estrogen Induced Human Breast Carcinogenesis. Proc. Am. Assoc. Cancer Res.46: 2097a, 2005.
  16. Russo, J. Estrogens as carcinogens in the human breast. Proc. Am. Assoc. Cancer Res.46:SY14-1, 2005.
  17. Vanegas, J.E., Russo, P.A., Russo, I.H., Russo, J. Estrogen and its metabolites alter the migratory behavior of human breast epithelial cells. Proc. Era of Hope, June 2005
  18. Russo, P.A., Lareef, M.H., Garber, J., Russo, I.H., Fernandez, S.V., Fernbaugh, R., Balsara, B., Sheriff, F., Balogh, G., Mailo, D., Heulings, R. Russo, J. A model of estrogen induced human breast carcinogenesis. Proc. Era of Hope, June 2005.
  19. Fernandez, S.V., Russo, I.H., Russo, J. Estrogen and its metabolites 4-Hydroxy estradiol and 2-Hydrox-yestradiol induce mutations in human breast epithelial cells. Proc. Era of Hope, June 2005.
  20. Chen, J.Q, Russo, P, Russo, IH, and Russo, J   ER shifts from mitochondria to nucleus during 17-estradiol induced neoplastic transformation of human breast epithelial cells. Proceeding of the Am. Assoc. Cancer Res. 47:2932a, 2006.
  21. Huang,Y., Fernandez,S.,  Goodwin, S.,  Russo, P.A., Russo, P.A.,  Sutter, T.R.,  Russo, J. Genomic profile of the estrogen induced neoplastic transformation of the human breast epithelial cell MCF10F.  Proceeding of the Am. Assoc. Cancer Res. 47:149a, 2006.
  22. Fernandez, S.V., Wu,Y-Z., Russs,I.H., Plass C., Russo, J. The role of DNA methylation in estrogen-induced transformation of human breast epithelial cells. Proc Am. Assoc. Cancer Res. 47: 1590a, 2006
  23. Saeed, M., Rogan, E., Cavalieri, E., Sheriff, F., Fernandez, S.V.,  Russo, J. Formation of the DNA depurinating N3Ade and N7Gua adducts of 4-Hydroxyestradiol by MCF10F cells cultured with the carcinogenic estrogen metabolite 4-Hydroxyestradiol. Proceeding of the Am. Assoc. Cancer Res. 47:1895a, 2006.
  24. Chen, JQ, Russo, PA, Russo, IH, and Russo, J. Mitochondria-to-nucleus shift of the estrogen receptor beta during estrogen-induced transformation of human breast epithelial cells. Proceeding Endocrine Society, 2006.
  25. Tiezzi, D.G., Fernandez, S.V., Huang, Y.,  Sutter, T., and Russo, J., Epithelial-mesenchymal transition during breast cancer progression. Proceeding of the Am. Assoc. Cancer Res., 2007.
  26. Chen, J-Q., Tiezzi, D., Russo, I.H., and Russo, J. Estrogen receptor beta is directly involved in 17-estradiol (E2)-induced synthesis of mitochondrial DNA (mtDNA)-encoded mitochondrial respiratory chain proteins. Proceeding of the Am. Assoc. Cancer Res., 2007.
  27. Fernandez, S.V., Russo, I.H. and Russo, J. Role of DNA-methylation in the branching pattern of Estrogen-Transformed Human Breast Epithelial Cells, Proceeding of the Am. Assoc. Cancer Res., 2007.
  28. Maria Luiza S Mello, Patricia Russo, Jose Russo, Benedicto C. Vidal DNA content and chromatin supraorganization change in estrogen-transformed human breast epithelial cells. Amsterdam meeting 2007.