The major goals of this project are:
- To provide tissue sections and pertinent clinical data to investigators.
- To construct tissue microarrays and further distribution to investigators.
The Fox Chase Breast Cancer Tissue Resource was initially one of four geographically diverse facilities from across the nation participating in the National Cancer Institute’s Cooperative Breast Cancer Tissue Resource. The other three institutions working in consortium with FCCC are Kaiser Permanente in Portland Oregon, University of Miami, and the University of Missouri. A computerized central database was maintained in Silver Spring, Maryland. The Fox Chase Breast Cancer Tissue Resource is a collaborative effort among the Hospital of the Fox Chase Cancer Center and eleven other Fox Chase Network Hospitals.
Main Publications Generated from this Project
- Russo, J. Differentiation and Pathogenesis of breast cancer. Women and Cancer 1: 14-21, 1998.
- Abdel-Rahman N. Zekri, Abeer A. Bahnassi, Betsy Bove, Yajue Huang, Irma H. Russo, André Rogatko, Sabry Shaarawy, Osama A. Shawki, Mohamed-Reda Hamza, Sherif Omer, Hussein M. Khaled. and Jose Russo. Allelic instability as a predictor of survival in breast cancer patients. International Journal of Oncology 15:757-767, 1999.
- Bahnassy, A.A., Zekri, A.R., Bove, B., Raafat, A., El-Bolkainy, M.N., Ali, N.M., Omar, S., Russo, J. The role of allelic imbalance at chromosome 2p16 in breast cancer progression. J. Egyptian Cancer Institute, 12:211-220, 2000.
- Fuqua, S.A.W., Russo, J., Shackney, S.E., Stearns, M.E. Estrogen, Estrogen Receptors and Selective Estrogen Receptor Modulators in Human Breast Cancer. Journal of Women’s Cancer 2:21-32, 2000.
- Fuqua, S.A., Russo, J., Shackney, S.E., Stearns, ME., Selective estrogen receptor modulators. An aid in unraveling the links between estrogen and breast cancer. Postgrad. Med. Spec No: 3-10, 2001.
- Glass, A.G., Donis-Keller, H., Mies, C., Russo, J., Zehnbauer, B., Taube, S., Aamodt, R. The cooperative breast cancer tissue resource: Archival Tissue for the investigation of tumor markers. Clinical Cancer Res 7(7):1843-1849, 2001.
- Meyer, J.S., Alvarez, C., Lister, K., Milikowski, C., Olson, N., Russo, I.H., Russo, J., Zehnbauer, B., Glass A., Parwaresch, R. Breast carcinoma malignancy grading by Bloom-Richardson system vs proliferation index: reproducibility of grade and advantages of proliferation index. Mod Pathol 18:1067-78, 2005.